HitPredict

Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	27187154, 35271311, 16169850
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000774 - adenyl-nucleotide exchange factor activity GO:0005829 - cytosol GO:0006457 - protein folding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 840
+	Ce
		247901 O61980_CAEEL (14-186): 5.24e-74: 232: 39.88		HSP1_CAEEL (2-603): 0: 811: 31.48
+	Hs
		323563 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		323559 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		HS71B_HUMAN (571-686): 1.59e-19: 95.5: 23.93
+	Hs
		323806 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		Q53FC7_HUMAN (587-690): 3.01e-16: 85.1: 22.86