HitPredict

Interactor 1: AP2A2 (O94973)
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene: AP2A2

Interactor 2: RNF12 (Q9NVW2)
E3 ubiquitin-protein ligase RLIM (EC 2.3.2.27) (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (RING finger protein 12) (RING-type E3 ubiquitin transferase RLIM) (Renal carcinoma antigen NY-REN-43)
Gene: RLIM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37132043
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 939 Hs			1 624
+	Hs
		344810 AP2A1_HUMAN (1-939): 0: 832: 78.47		RNF12_HUMAN (1-624): 1.18e-119: 370: 100.00
+	Hs
		323805 AP2A2_HUMAN (1-939): 0: 884: 100.00		RNF6_HUMAN (1-615): 2.66e-93: 303: 38.29
+	Hs
		323775 AP2A2_HUMAN (1-939): 0: 884: 100.00		RN126_HUMAN (364-621): 4.24e-34: 134: 18.08
+	Hs
		989136 AP2B1_HUMAN (36-933): 0: 607: 16.62		RNF12_HUMAN (1-624): 1.18e-119: 370: 100.00
+	Hs
		302290 AP2A1_HUMAN (1-939): 0: 832: 78.47		RNF8_HUMAN (330-614): 3.81e-34: 138: 11.15
+	Hs
		302468 AP2B1_HUMAN (36-933): 0: 607: 16.62		RNF8_HUMAN (330-614): 3.81e-34: 138: 11.15
+	Hs
		220456 AP1G1_HUMAN (1-811): 0: 616: 25.12		RNF13_HUMAN (550-618): 7.05e-30: 123: 42.86
+	Hs
		225835 AP1G1_HUMAN (1-811): 0: 616: 25.12		RN149_HUMAN (524-617): 1.49e-28: 120: 29.00
+	Hs
		220459 AP1G2_HUMAN (13-816): 0: 554: 25.83		RNF13_HUMAN (550-618): 7.05e-30: 123: 42.86
+	Hs
		158736 AP3D1_HUMAN (11-478): 3.34e-33: 140: 23.51		RNF13_HUMAN (550-618): 7.05e-30: 123: 42.86