Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: MLP3A (Q9H492)
Microtubule-associated protein 1 light chain 3 alpha (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (Microtubule-associated proteins 1A/1B light chain 3A) (MAP1A/MAP1B LC3 A) (MAP1A/MAP1B light chain 3 A)
Gene: MAP1LC3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 16303767, 36576150, 29033323, 25601754, 31857589, 20562859, 11096062
Identification Methods pull down, enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG8~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0000423 - mitophagy
GO:0005829 - cytosol
GO:0006995 - cellular response to nitrogen starvation
GO:0009267 - cellular response to starvation
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 703
Hs

1 121
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+ Mm
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+ At
+ At
+ Dm
+ Ce
+ Ce
+ Sc
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+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025