HitPredict

Interactor 1: ATG7 (Q9D906)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (mAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: GBRAP (Q9DCD6)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein)
Gene: Gabarap

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11890701
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ATG8~ThiF
Common GO terms	GO:0005930 - axoneme GO:0006914 - autophagy GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 698 Mm			1 117
+	Mm
		952401 ATG7_MOUSE (1-698): 0: 960: 100.00		GBRL2_MOUSE (1-117): 2.76e-58: 176: 57.27
+	Hs
		334166 ATG7_HUMAN (2-698): 0: 943: 93.12		GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27
+	Hs
		327708 ATG7_HUMAN (2-698): 0: 943: 93.12		GBRAP_HUMAN (1-117): 8.09e-57: 173: 100.00
+	Hs
		334240 ATG7_HUMAN (2-698): 0: 943: 93.12		GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07
+	Mm
		1362239 ATG7_MOUSE (1-698): 0: 960: 100.00		MLP3A_MOUSE (5-117): 2.3e-45: 144: 30.44
+	Mm
		1423747 ATG7_MOUSE (1-698): 0: 960: 100.00		MLP3B_MOUSE (2-116): 2.1e-44: 142: 30.77
+	Hs
		334242 ATG7_HUMAN (2-698): 0: 943: 93.12		MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44
+	Hs
		334234 ATG7_HUMAN (2-698): 0: 943: 93.12		MLP3C_HUMAN (5-116): 1.16e-44: 143: 38.60
+	Hs
		334239 ATG7_HUMAN (2-698): 0: 943: 93.12		MLP3B_HUMAN (2-117): 3.56e-44: 141: 30.51
+	At
		1376074 ATG7_ARATH (9-686): 0: 775: 45.15		ATG8D_ARATH (3-117): 3.42e-62: 186: 56.52
+	At
		1354489 ATG7_ARATH (9-686): 0: 775: 45.15		ATG8F_ARATH (2-117): 1.06e-61: 185: 58.62
+	Dm
		1263327 Q7JY94_DROME (9-696): 0: 765: 39.69		Q9W2S2_DROME (1-117): 5.31e-58: 176: 91.45
+	Ce
		109695 G5EBK4_CAEEL (11-686): 0: 680: 40.56		LGG1_CAEEL (1-116): 2.48e-55: 170: 83.62
+	Sc
		795335 ATG7_YEAST (7-697): 0: 654: 38.02		ATG8_YEAST (1-116): 9.22e-59: 178: 55.17
+	Ce
		109698 G5EBK4_CAEEL (11-686): 0: 680: 40.56		LGG2_CAEEL (4-116): 4.61e-39: 128: 33.04
+	Sc
		795332 UBA4_YEAST (314-540): 1.83e-51: 186: 19.31		ATG8_YEAST (1-116): 9.22e-59: 178: 55.17
+	Hs
		952335 UBA5_HUMAN (322-590): 8.5e-46: 170: 18.25		GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27
+	Hs
		328145 UBA5_HUMAN (322-590): 8.5e-46: 170: 18.25		GBRAP_HUMAN (1-117): 8.09e-57: 173: 100.00
+	Hs
		1417410 UBA5_HUMAN (322-590): 8.5e-46: 170: 18.25		MLP3C_HUMAN (5-116): 1.16e-44: 143: 38.60
+	Hs
		1428343 UBA5_HUMAN (322-590): 8.5e-46: 170: 18.25		MLP3B_HUMAN (2-117): 3.56e-44: 141: 30.51