Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1
Interactor 2: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12445832 |
| Identification Methods | protein kinase assay, anti tag coimmunoprecipitation |
| Interaction Type | physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, PH~SH3_1, SH3_1~SH3_1 |
| Common GO terms | GO:0004713 - protein tyrosine kinase activity GO:0004715 - non-membrane spanning protein tyrosine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 5 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
