HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: LRC31 (Q6UY01)
Leucine-rich repeat-containing protein 31
Gene: LRRC31

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33005030
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 552
+	Hs
		1071001 ERBB4_HUMAN (1-1199): 0: 1137: 49.46		LRRC7_HUMAN (83-464): 3.1e-22: 103: 20.65
+	Hs
		383940 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		LRRC7_HUMAN (83-464): 3.1e-22: 103: 20.65
+	Hs
		601980 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		LRRC7_HUMAN (83-464): 3.1e-22: 103: 20.65
+	At
		1338064 TMK3_ARATH (346-984): 2.89e-145: 464: 16.13		RGI1_ARATH (59-547): 3.92e-62: 223: 17.92
+	At
		83704 Y5182_ARATH (429-1004): 1.84e-136: 439: 14.89		Y4361_ARATH (36-417): 2.29e-41: 162: 16.67
+	At
		84729 F4I065_ARATH (417-1003): 2.31e-135: 436: 15.92		Y4361_ARATH (36-417): 2.29e-41: 162: 16.67
+	At
		83702 Y5182_ARATH (429-1004): 1.84e-136: 439: 14.89		RGI3_ARATH (59-368): 2.98e-36: 146: 15.86
+	At
		83711 Y5182_ARATH (429-1004): 1.84e-136: 439: 14.89		RLK5_ARATH (21-390): 5.15e-36: 145: 15.30
+	At
		812854 Q8GY50_ARATH (341-1019): 2.48e-135: 438: 15.57		RLK5_ARATH (21-390): 5.15e-36: 145: 15.30
+	At
		83724 Y5182_ARATH (429-1004): 1.84e-136: 439: 14.89		PXC2_ARATH (22-369): 1.15e-35: 144: 17.43
+	At
		95366 F4I065_ARATH (417-1003): 2.31e-135: 436: 15.92		RGI4_ARATH (219-552): 1.02e-33: 138: 18.81
+	At
		83729 Y5182_ARATH (429-1004): 1.84e-136: 439: 14.89		CLV1_ARATH (262-552): 5.58e-30: 127: 16.38
+	At
		85102 F4I065_ARATH (417-1003): 2.31e-135: 436: 15.92		RGI2_ARATH (17-301): 2.93e-30: 128: 16.29
+	At
		83721 Y5182_ARATH (429-1004): 1.84e-136: 439: 14.89		Y3804_ARATH (310-552): 2.55e-28: 122: 17.70
+	At
		84503 TMK3_ARATH (346-984): 2.89e-145: 464: 16.13		GSO1_ARATH (22-212): 5.55e-15: 80.4: 15.54
+	At
		1341092 TMK3_ARATH (346-984): 2.89e-145: 464: 16.13		BAME2_ARATH (48-200): 5.13e-14: 77.3: 11.39
+	At
		221803 TMK3_ARATH (346-984): 2.89e-145: 464: 16.13		BAME1_ARATH (48-200): 1.27e-13: 76.1: 13.92
+	At
		84463 TMK1_ARATH (345-984): 1.18e-139: 449: 15.52		GSO1_ARATH (22-212): 5.55e-15: 80.4: 15.54
+	At
		221760 TMK1_ARATH (345-984): 1.18e-139: 449: 15.52		BAME1_ARATH (48-200): 1.27e-13: 76.1: 13.92
+	At
		83707 Y5182_ARATH (429-1004): 1.84e-136: 439: 14.89		BAME1_ARATH (48-200): 1.27e-13: 76.1: 13.92