Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28

Interactor 2: PTK2 (P47116)
Serine/threonine-protein kinase PTK2/STK2 (EC 2.7.11.1)
Gene: PTK2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.807

The method score is based on:

Property Details
Experiments 14574415, 24019491
Identification Methods protein kinase assay, enzymatic study, protein complementation assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 298
Sc

1 818
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Mm
+ At
+ At
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024