HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: K1H1 (Q15323)
Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)
Gene: KRT31

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 416
+	Hs
		349046 LATS1_HUMAN (1-1130): 0: 925: 100.00		K1C17_HUMAN (49-367): 1.14e-116: 348: 59.88
+	Hs
		348944 LATS1_HUMAN (1-1130): 0: 925: 100.00		K1C16_HUMAN (54-382): 2.64e-115: 347: 58.36
+	Hs
		349145 LATS1_HUMAN (1-1130): 0: 925: 100.00		K2C73_HUMAN (9-370): 1.03e-98: 306: 25.00
+	Hs
		349003 LATS1_HUMAN (1-1130): 0: 925: 100.00		K2C6C_HUMAN (19-391): 1.61e-84: 270: 24.27
+	Hs
		348956 LATS1_HUMAN (1-1130): 0: 925: 100.00		K2C5_HUMAN (19-370): 7.66e-84: 269: 25.71
+	Hs
		348924 LATS1_HUMAN (1-1130): 0: 925: 100.00		K2C6A_HUMAN (19-391): 4.52e-83: 266: 24.27
+	Hs
		1146219 ST38L_HUMAN (627-1089): 1.01e-161: 489: 40.82		K1H1_HUMAN (1-416): 2.67e-90: 280: 100.00
+	Hs
		566104 AKT1_HUMAN (595-1079): 1.92e-140: 434: 24.60		K1C10_HUMAN (52-361): 3.2e-95: 298: 56.01
+	Hs
		1127803 AKT3_HUMAN (603-1079): 9.43e-143: 440: 24.64		K1H2_HUMAN (5-406): 1.12e-87: 275: 69.15
+	Hs
		728234 AKT1_HUMAN (595-1079): 1.92e-140: 434: 24.60		K1H2_HUMAN (5-406): 1.12e-87: 275: 69.15
+	Hs
		566397 MRCKA_HUMAN (694-1047): 2.93e-66: 248: 39.06		K2C5_HUMAN (19-370): 7.66e-84: 269: 25.71
+	Hs
		1145997 Q6PJG3_HUMAN (1-117): 2.14e-61: 207: 99.15		K1H1_HUMAN (1-416): 2.67e-90: 280: 100.00