HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: OCRL (Q01968)
Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)
Gene: OCRL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 901
+	Hs
		968144 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		918850 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		968218 RAB1B_HUMAN (4-187): 1.21e-73: 221: 32.47		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		914016 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		896610 RAB14_HUMAN (4-184): 3.77e-72: 218: 29.51		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		845848 RAB13_HUMAN (4-186): 7.7e-72: 217: 36.76		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		968196 RAB1C_HUMAN (4-187): 1.48e-71: 216: 33.51		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Rn
		1157320 RAB1A_RAT (4-187): 7.4e-74: 222: 34.36		R9PXS2_RAT (14-901): 0: 1038: 93.81
+	Rn
		896707 RAB14_RAT (4-184): 3.77e-72: 218: 29.51		R9PXS2_RAT (14-901): 0: 1038: 93.81
+	Dm
		185463 O18332_DROME (4-187): 9.68e-72: 217: 32.31		O46094_DROME (209-900): 1.12e-177: 537: 33.15
+	Hs
		203195 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SYNJ1_HUMAN (218-733): 8.18e-121: 403: 24.37