HitPredict

Interactor 1: O96692 (O96692)
small monomeric GTPase (EC 3.6.5.2)
Gene: Rap2l

Interactor 2: SPRI (Q8MQW8)
Protein sprint (SH2 poly-proline-containing Ras-interactor protein)
Gene: SPRI

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	15710747
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RA~Ras, Ras~VPS9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 182 Dm			1 1789
+	Hs
		976643 RB11A_HUMAN (4-176): 1.49e-74: 224: 32.76		RABX5_HUMAN (1388-1685): 9.48e-76: 263: 18.85
+	Hs
		557196 RAB2A_HUMAN (4-170): 1.12e-75: 227: 33.93		SRC_HUMAN (330-574): 8.22e-56: 206: 16.86
+	Hs
		557200 RB11A_HUMAN (4-176): 1.49e-74: 224: 32.76		SRC_HUMAN (330-574): 8.22e-56: 206: 16.86
+	Hs
		557324 RB11B_HUMAN (4-176): 2.06e-73: 221: 32.76		SRC_HUMAN (330-574): 8.22e-56: 206: 16.86
+	Hs
		959367 RAP1B_HUMAN (1-182): 4.04e-78: 232: 56.52		RIN3_HUMAN (458-969): 1.85e-49: 194: 20.19
+	Hs
		1216704 Q5U0I6_HUMAN (4-176): 1.08e-76: 229: 33.33		RIN3_HUMAN (458-969): 1.85e-49: 194: 20.19
+	Hs
		981323 RAB1A_HUMAN (4-176): 1.08e-76: 229: 33.33		RIN3_HUMAN (458-969): 1.85e-49: 194: 20.19
+	Hs
		76307 B4DMN1_HUMAN (4-176): 4.91e-75: 227: 32.76		RIN3_HUMAN (458-969): 1.85e-49: 194: 20.19
+	Hs
		956413 RAB2A_HUMAN (4-170): 1.12e-75: 227: 33.93		RIN3_HUMAN (458-969): 1.85e-49: 194: 20.19
+	Hs
		463042 RAB2A_HUMAN (4-170): 1.12e-75: 227: 33.93		YES_HUMAN (337-574): 2.32e-48: 184: 15.45
+	Hs
		463048 RB11A_HUMAN (4-176): 1.49e-74: 224: 32.76		YES_HUMAN (337-574): 2.32e-48: 184: 15.45
+	Hs
		373749 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		SRC_HUMAN (330-574): 8.22e-56: 206: 16.86
+	Hs
		959329 RAP1B_HUMAN (1-182): 4.04e-78: 232: 56.52		RIN1_HUMAN (421-773): 8.86e-25: 114: 23.45
+	Hs
		959439 RAP2B_HUMAN (1-182): 1.45e-76: 228: 67.76		RIN1_HUMAN (421-773): 8.86e-25: 114: 23.45
+	Hs
		373909 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		GRB10_HUMAN (105-566): 1.17e-49: 189: 14.23
+	Hs
		373734 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		YES_HUMAN (337-574): 2.32e-48: 184: 15.45
+	Hs
		518598 RAP2A_HUMAN (1-178): 2.2e-71: 215: 69.66		RIN1_HUMAN (421-773): 8.86e-25: 114: 23.45
+	Hs
		374102 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		RIN2_HUMAN (405-805): 2.19e-40: 165: 21.16
+	Hs
		319042 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		K0754_HUMAN (560-1141): 3.58e-25: 116: 15.63
+	Hs
		373918 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		RIN1_HUMAN (421-773): 8.86e-25: 114: 23.45