HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: ARP4 (P80428)
Actin-related protein 4 (Actin-like protein ARP4) (Actin-like protein 4)
Gene: ARP4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	10436015, 10911987, 22977180, 21179020
Identification Methods	coimmunoprecipitation, two hybrid, affinity chromatography technology, far western blotting, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 489
+	Sc
		356651 H4_YEAST (1-103): 5.28e-47: 147: 100.00		ACT_YEAST (301-488): 9.89e-73: 236: 27.51
+	Hs
		891667 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		ACTB_HUMAN (274-488): 4.21e-65: 216: 23.87
+	Hs
		917088 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		ACTG_HUMAN (274-488): 8.57e-65: 215: 23.87
+	Hs
		917091 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		ACTS_HUMAN (274-488): 4.25e-64: 214: 23.42
+	Sc
		356799 H4_YEAST (1-103): 5.28e-47: 147: 100.00		ARP7_YEAST (17-482): 1.62e-22: 102: 23.35
+	Hs
		331484 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		ACL6A_HUMAN (301-482): 7.4e-22: 99.8: 33.67