HitPredict

Interactor 1: CRP (P02741)
C-reactive protein [Cleaved into: C-reactive protein(1-205)]
Gene: CRP

Interactor 2: FHR4 (Q92496)
Complement factor H-related protein 4 (FHR-4)
Gene: CFHR4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	19084272, 20042240
Identification Methods	solid phase assay, surface plasmon resonance, enzyme linked immunosorbent assay, peptide array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 224 Hs			1 578
+	Hs
		362382 CRP_HUMAN (1-224): 1.8e-107: 310: 100.00		FHR3_HUMAN (1-323): 5.15e-65: 217: 48.32
+	Hs
		362420 SAMP_HUMAN (1-223): 3.92e-95: 278: 51.79		C4BPA_HUMAN (8-332): 9.15e-40: 155: 16.22
+	Hs
		362354 CRP_HUMAN (1-224): 1.8e-107: 310: 100.00		CFAH_HUMAN (452-578): 5.78e-09: 61.4: 17.42
+	Hs
		555713 PTX3_HUMAN (26-214): 8.79e-66: 209: 25.89		LYAM3_HUMAN (9-335): 1.4e-40: 159: 13.33
+	Hs
		441703 PTX3_HUMAN (26-214): 8.79e-66: 209: 25.89		CFAH_HUMAN (452-578): 5.78e-09: 61.4: 17.42