HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33731348, 34591612, 21182205
Identification Methods	affinity chromatography technology, cosedimentation through density gradient, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0019901 - protein kinase binding GO:0032991 - protein-containing complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 1675
+	Hs
		377253 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		369239 ESR1_HUMAN (1-595): 0: 599: 100.00		CLH2_HUMAN (1-1634): 0: 2869: 85.01
+	Hs
		487338 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		CLH1_HUMAN (1-1675): 0: 3132: 100.00