HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: AK17A (Q02040)
A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A)
Gene: AKAP17A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31527615, unassigned1953
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription GO:0007165 - signal transduction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 695
+	Hs
		968712 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		AK17A_HUMAN (1-695): 1.25e-151: 457: 100.00
+	Hs
		370685 ESR1_HUMAN (1-595): 0: 599: 100.00		TAOK2_HUMAN (205-544): 9.53e-38: 153: 15.32
+	Hs
		370586 ESR1_HUMAN (1-595): 0: 599: 100.00		ITSN2_HUMAN (226-666): 1.26e-21: 102: 14.03
+	Hs
		1269904 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TAOK2_HUMAN (205-544): 9.53e-38: 153: 15.32
+	Hs
		1269784 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		ITSN2_HUMAN (226-666): 1.26e-21: 102: 14.03
+	Hs
		377746 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		ITSN2_HUMAN (226-666): 1.26e-21: 102: 14.03