HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: S12A7 (Q9Y666)
Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4)
Gene: SLC12A7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30442766, 30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1083
+	Hs
		376155 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		1145201 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		376100 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		S12A4_HUMAN (1-1083): 0: 1104: 69.39
+	Hs
		376067 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		S12A6_HUMAN (14-1083): 0: 1103: 69.47
+	Hs
		1145174 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		S12A4_HUMAN (1-1083): 0: 1104: 69.39
+	Hs
		1145158 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		S12A6_HUMAN (14-1083): 0: 1103: 69.47
+	Hs
		374283 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		S12A4_HUMAN (1-1083): 0: 1104: 69.39
+	Hs
		375323 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		S12A2_HUMAN (25-1083): 0: 819: 21.97
+	Hs
		933406 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		S12A2_HUMAN (25-1083): 0: 819: 21.97
+	Hs
		373857 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		S12A2_HUMAN (25-1083): 0: 819: 21.97
+	Hs
		374501 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		S12A2_HUMAN (25-1083): 0: 819: 21.97
+	Hs
		955999 RAB8A_HUMAN (4-185): 1.75e-84: 249: 36.02		S12A9_HUMAN (116-911): 9.14e-170: 524: 25.12
+	Hs
		375315 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		CTR2_HUMAN (160-607): 1.86e-90: 305: 16.04
+	Hs
		912672 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		CTR2_HUMAN (160-607): 1.86e-90: 305: 16.04
+	Hs
		373852 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		CTR2_HUMAN (160-607): 1.86e-90: 305: 16.04
+	Hs
		375221 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		CTR1_HUMAN (160-603): 3.86e-85: 290: 14.35
+	Hs
		722459 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		CTR1_HUMAN (160-603): 3.86e-85: 290: 14.35
+	Hs
		373795 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		CTR1_HUMAN (160-603): 3.86e-85: 290: 14.35
+	Hs
		374425 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		CTR1_HUMAN (160-603): 3.86e-85: 290: 14.35
+	Hs
		211101 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		CTR4_HUMAN (164-603): 1.33e-33: 140: 17.42