Interactor 1: LDLR (P01130)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Interactor 2: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.671

The method score is based on:

Property Details
Experiments 39499777, 20030366, 24447298
Identification Methods proximity labelling technology, pull down, nuclear magnetic resonance, surface plasmon resonance
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006898 - receptor-mediated endocytosis
and 16 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 860
Hs

1 317
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025