HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38580884
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0048144 - fibroblast proliferation GO:0048147 - negative regulation of fibroblast proliferation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 669
+	Hs
		386342 P53_HUMAN (1-393): 0: 619: 100.00		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Mm
		356850 P53_MOUSE (1-393): 0: 589: 77.35		SMCA4_MOUSE (18-526): 1.74e-30: 130: 12.69
+	Hs
		387576 P53_HUMAN (1-393): 0: 619: 100.00		MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02
+	Hs
		387710 P53_HUMAN (1-393): 0: 619: 100.00		MYH13_HUMAN (161-669): 3.57e-13: 75.4: 11.94
+	Hs
		386617 P53_HUMAN (1-393): 0: 619: 100.00		CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88
+	Hs
		387815 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32
+	Hs
		386769 P53_HUMAN (1-393): 0: 619: 100.00		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		386909 P53_HUMAN (1-393): 0: 619: 100.00		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		148271 P53_HUMAN (1-393): 0: 619: 100.00		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36