HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: ZBT17 (Q13105)
Zinc finger and BTB domain-containing protein 17 (Myc-interacting zinc finger protein 1) (Miz-1) (Zinc finger protein 151) (Zinc finger protein 60)
Gene: ZBTB17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	21123453, 21908575, 26766587
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 464 Hs			1 803
+	Hs
		346669 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		ZBT17_HUMAN (1-803): 0: 671: 100.00
+	Mm
		348425 MYC_MOUSE (5-463): 1.09e-71: 235: 33.95		ZBT17_MOUSE (1-803): 0: 654: 91.28
+	Hs
		898113 MAX_HUMAN (363-463): 2.41e-25: 103: 33.65		ZBT17_HUMAN (1-803): 0: 671: 100.00
+	Hs
		379980 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		ZN629_HUMAN (684-780): 2.58e-12: 72.8: 23.71