HitPredict

Interactor 1: DRA (P01903)
HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA)
Gene: HLA-DRA

Interactor 2: GDC (P16260)
Solute carrier family 25 member 16 (Graves disease autoantigen) (GDA) (Graves disease carrier protein) (GDC) (Graves' didease protein) (hGP) (Mitochondrial solute carrier protein homolog)
Gene: SLC25A16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 254 Hs			1 332
+	Hs
		593570 DPA1_HUMAN (1-254): 8.23e-77: 235: 58.66		GDC_HUMAN (26-332): 5.03e-112: 330: 100.00
+	Hs
		380313 DRA_HUMAN (1-254): 4.8e-87: 260: 100.00		S2542_HUMAN (37-326): 2.55e-54: 182: 39.80
+	Hs
		380300 DRA_HUMAN (1-254): 4.8e-87: 260: 100.00		KMCP1_HUMAN (130-332): 7.43e-36: 133: 25.36
+	Hs
		409553 DPB1_HUMAN (5-253): 7.24e-72: 222: 25.19		ADT3_HUMAN (126-329): 9.25e-33: 124: 23.33
+	Hs
		380251 DRA_HUMAN (1-254): 4.8e-87: 260: 100.00		ADT1_HUMAN (234-329): 5.83e-12: 67.2: 23.23
+	Hs
		380402 DQA1_HUMAN (1-254): 1.8e-86: 259: 52.94		ADT1_HUMAN (234-329): 5.83e-12: 67.2: 23.23
+	Hs
		551948 DPA1_HUMAN (1-254): 8.23e-77: 235: 58.66		ADT1_HUMAN (234-329): 5.83e-12: 67.2: 23.23
+	Hs
		409552 DPB1_HUMAN (5-253): 7.24e-72: 222: 25.19		ADT1_HUMAN (234-329): 5.83e-12: 67.2: 23.23
+	Hs
		380584 DRB1_HUMAN (1-222): 3.6e-69: 215: 19.91		ADT4_HUMAN (223-330): 5.91e-13: 70.3: 22.52
+	Hs
		379847 HLAB_HUMAN (32-219): 1.14e-68: 217: 18.09		ADT1_HUMAN (234-329): 5.83e-12: 67.2: 23.23
+	Hs
		380610 DQB1_HUMAN (1-222): 5.43e-69: 214: 19.05		ADT1_HUMAN (234-329): 5.83e-12: 67.2: 23.23