HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: HMO1 (Q03973)
High mobility group protein 1 (High spontaneous mutagenesis protein 2)
Gene: HMO1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	16429126, 16554755, 22199229
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 246
+	Hs
		979908 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		PB1_HUMAN (23-216): 2.04e-31: 124: 15.98
+	Hs
		980371 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		HM20A_HUMAN (19-198): 3.09e-31: 119: 19.13
+	Hs
		979555 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		SSRP1_HUMAN (21-234): 1.05e-28: 115: 18.34
+	Hs
		318471 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		TOX4_HUMAN (2-186): 8.67e-28: 112: 16.49
+	Sc
		381997 H4_YEAST (1-103): 5.31e-47: 147: 100.00		IXR1_YEAST (86-196): 1.72e-22: 97.7: 22.52
+	Ce
		144952 H4_CAEEL (18-103): 1.71e-41: 133: 89.54		SSP1B_CAEEL (20-227): 2.02e-25: 106: 16.20
+	Mm
		872964 H4_MOUSE (18-103): 1.93e-41: 133: 90.70		SOX2_MOUSE (73-194): 1.94e-25: 103: 16.39
+	Hs
		980458 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		HM20B_HUMAN (64-186): 8.27e-25: 101: 20.93
+	Sc
		381822 H4_YEAST (1-103): 5.31e-47: 147: 100.00		NHP6B_YEAST (80-183): 1.32e-20: 85: 21.15
+	Sc
		381821 H4_YEAST (1-103): 5.31e-47: 147: 100.00		NHP6A_YEAST (89-183): 1.33e-19: 82.3: 22.11
+	Hs
		186639 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		HMGB3_HUMAN (94-196): 5.6e-20: 86.6: 25.96
+	Hs
		481204 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		HMGB1_HUMAN (83-189): 5.24e-19: 84.3: 21.50