Interactor 1: CRYAA (P02470)
Alpha-crystallin A chain [Cleaved into: Alpha-crystallin A(1-172); Alpha-crystallin A(1-168)]
Gene: CRYAA
Interactor 2: CRYAB (P02510)
Alpha-crystallin B chain (Alpha(B)-crystallin)
Gene: CRYAB
Species: Bos taurus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.721 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19651604 |
| Identification Methods | cosedimentation in solution, transmission electron microscopy, molecular sieving, dynamic light scattering |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Crystallin~Crystallin, Crystallin~HSP20, HSP20~HSP20 |
| Common GO terms | GO:0005212 - structural constituent of eye lens GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0009408 - response to heat GO:0032387 - negative regulation of intracellular transport and 4 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025