Interactor 1: CRYAA (P02489)
Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4) (Heat shock protein family B member 4) [Cleaved into: Alpha-crystallin A(1-172); Alpha-crystallin A(1-168); Alpha-crystallin A(1-162)]
Gene: CRYAA
Interactor 2: HSPB2 (Q16082)
Heat shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP) (Heat shock protein family B member 2)
Gene: HSPB2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.713 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12601044 |
| Identification Methods | two hybrid, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Crystallin~Crystallin, Crystallin~HSP20, HSP20~HSP20 |
| Common GO terms | GO:0005212 - structural constituent of eye lens GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0009408 - response to heat and 3 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
