Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 25921289
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005769 - early endosome
GO:0005886 - plasma membrane
GO:0008285 - negative regulation of cell population proliferation
GO:0009986 - cell surface
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 796
Hs

1 272
+ Hs
+ Hs
+ Hs
+ Rn
+ Mm

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Last updated: 15 Jul 2024