HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: FKBP3 (Q00688)
Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)
Gene: FKBP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FKBP_C~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 224
+	Hs
		384676 NTRK1_HUMAN (1-796): 0: 621: 100.00		FKBP4_HUMAN (74-224): 6.73e-17: 80.5: 24.68
+	Hs
		384787 NTRK1_HUMAN (1-796): 0: 621: 100.00		FKBP5_HUMAN (76-224): 5.61e-14: 72.1: 23.03
+	Rn
		102483 INSR_RAT (493-777): 7.31e-66: 241: 41.95		G3V6L9_RAT (1-224): 5.27e-100: 291: 95.09
+	Hs
		972518 DDR2_HUMAN (499-781): 3.37e-72: 254: 44.55		FKBP4_HUMAN (74-224): 6.73e-17: 80.5: 24.68
+	Hs
		537736 INSRR_HUMAN (493-782): 6.64e-66: 241: 42.91		FKBP5_HUMAN (76-224): 5.61e-14: 72.1: 23.03
+	At
		1341059 BRL2_ARATH (140-396): 2.09e-17: 89.3: 10.49		FK201_ARATH (130-221): 1.1e-14: 71.2: 47.31
+	Hs
		169174 MUSK_HUMAN (171-374): 2.86e-13: 75.8: 18.61		FKBP5_HUMAN (76-224): 5.61e-14: 72.1: 23.03