HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030424 - axon GO:0043025 - neuronal cell body
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 1278
+	Hs
		385569 NTRK1_HUMAN (1-796): 0: 621: 100.00		KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85
+	Hs
		385396 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBCB_HUMAN (19-96): 2.34e-32: 128: 46.91
+	Hs
		384385 NTRK1_HUMAN (1-796): 0: 621: 100.00		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Hs
		384981 NTRK1_HUMAN (1-796): 0: 621: 100.00		MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64
+	Hs
		384384 NTRK1_HUMAN (1-796): 0: 621: 100.00		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		384210 NTRK1_HUMAN (1-796): 0: 621: 100.00		DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64
+	Hs
		994632 DDR1_HUMAN (507-778): 1.77e-67: 242: 45.49		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		665375 EPHA3_HUMAN (262-788): 8.75e-112: 365: 26.64		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		725268 ALK_HUMAN (505-790): 8.72e-63: 231: 42.07		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Hs
		725069 ALK_HUMAN (505-790): 8.72e-63: 231: 42.07		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54