HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: K2C5 (P13647)
Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)
Gene: KRT5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35474131, 38580884
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 590
+	Hs
		386217 P53_HUMAN (1-393): 0: 619: 100.00		K22E_HUMAN (140-484): 3.01e-174: 509: 71.88
+	Hs
		385920 P53_HUMAN (1-393): 0: 619: 100.00		K2C8_HUMAN (140-516): 1.46e-162: 474: 69.23
+	Hs
		380435 P53_HUMAN (1-393): 0: 619: 100.00		K2C6B_HUMAN (2-503): 6.66e-84: 274: 79.08
+	Hs
		387010 P53_HUMAN (1-393): 0: 619: 100.00		K2C1B_HUMAN (36-499): 1.21e-66: 229: 60.35
+	Hs
		387220 P53_HUMAN (1-393): 0: 619: 100.00		KRT35_HUMAN (52-526): 5.44e-65: 221: 23.37
+	Hs
		531632 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		K2C5_HUMAN (1-590): 4.15e-92: 296: 100.00
+	Hs
		821689 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		K2C6C_HUMAN (2-503): 1.6e-83: 273: 78.69