HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	19933256, 22653443, 18812399
Identification Methods	coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030971 - receptor tyrosine kinase binding GO:0042149 - cellular response to glucose starvation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 247
+	Hs
		386446 P53_HUMAN (1-393): 0: 619: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		386182 P53_HUMAN (1-393): 0: 619: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		386482 P53_HUMAN (1-393): 0: 619: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		386139 P53_HUMAN (1-393): 0: 619: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		386183 P53_HUMAN (1-393): 0: 619: 100.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Mm
		250864 P53_MOUSE (1-393): 0: 589: 77.35		1433S_MOUSE (2-236): 1.38e-95: 281: 65.96
+	Hs
		684322 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16