HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: SRCAP (Q6ZRS2)
Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)
Gene: SRCAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38580884
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 3230
+	Hs
		386746 P53_HUMAN (1-393): 0: 619: 100.00		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		386152 P53_HUMAN (1-393): 0: 619: 100.00		SMCA1_HUMAN (2003-2406): 8.09e-92: 327: 26.49
+	Hs
		229278 P53_HUMAN (1-393): 0: 619: 100.00		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Hs
		387557 P53_HUMAN (1-393): 0: 619: 100.00		CHD8_HUMAN (2021-2361): 3.76e-67: 256: 28.57
+	Hs
		386342 P53_HUMAN (1-393): 0: 619: 100.00		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22
+	Hs
		387315 P53_HUMAN (1-393): 0: 619: 100.00		EP400_HUMAN (1085-1716): 1.74e-11: 73: 13.39
+	Mm
		356875 P53_MOUSE (1-393): 0: 589: 77.35		EP400_MOUSE (1024-1716): 9.22e-10: 67.2: 13.77
+	Mm
		356850 P53_MOUSE (1-393): 0: 589: 77.35		SMCA4_MOUSE (1022-1379): 7.86e-09: 64.2: 11.67