HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: DZIP3 (Q86Y13)
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)
Gene: DZIP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	27249653, 36841324
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1208
+	Hs
		386915 P53_HUMAN (1-393): 0: 619: 100.00		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Hs
		148271 P53_HUMAN (1-393): 0: 619: 100.00		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		387172 P53_HUMAN (1-393): 0: 619: 100.00		RN128_HUMAN (1112-1206): 2.54e-21: 100: 26.73
+	Hs
		387815 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (528-1066): 1.54e-15: 84.6: 10.97
+	Hs
		387017 P53_HUMAN (1-393): 0: 619: 100.00		SYVN1_HUMAN (1108-1192): 8.82e-15: 80.9: 32.58
+	Mm
		356888 P53_MOUSE (1-393): 0: 589: 77.35		RN128_MOUSE (1112-1206): 3.31e-21: 99.9: 26.73
+	Dm
		1213224 Q8IMZ4_DROME (124-325): 1.54e-78: 252: 24.31		Q9VGI6_DROME (942-1204): 1.97e-29: 129: 17.02
+	Dm
		1341773 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		Q9VGI6_DROME (942-1204): 1.97e-29: 129: 17.02
+	Dm
		1279545 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		HRD1_DROME (1130-1207): 4.86e-21: 101: 35.90