HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: K2C79 (Q5XKE5)
Keratin, type II cytoskeletal 79 (Cytokeratin-79) (CK-79) (Keratin-6-like) (Keratin-6L) (Keratin-79) (K79) (Type-II keratin Kb38)
Gene: KRT79

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 535
+	Hs
		395323 ESR1_HUMAN (1-595): 0: 599: 100.00		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		396420 ESR1_HUMAN (1-595): 0: 599: 100.00		K2C1B_HUMAN (36-476): 1.42e-81: 267: 59.48
+	Hs
		395464 ESR1_HUMAN (1-595): 0: 599: 100.00		K2C4_HUMAN (5-476): 1.01e-68: 231: 63.10
+	Hs
		396640 ESR1_HUMAN (1-595): 0: 599: 100.00		KRT35_HUMAN (53-457): 2.36e-63: 215: 24.44
+	Hs
		652459 NR4A1_HUMAN (64-549): 2.82e-105: 331: 24.54		K22E_HUMAN (114-460): 1.25e-156: 462: 70.03
+	Hs
		227253 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		KRT86_HUMAN (5-514): 1.06e-89: 285: 42.75
+	Hs
		341825 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		K2C75_HUMAN (3-471): 1.45e-88: 284: 62.26
+	Hs
		1007533 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		KRT85_HUMAN (2-509): 5.86e-88: 281: 44.49
+	Hs
		1135581 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		K2C72_HUMAN (23-525): 5.49e-77: 253: 52.95
+	Hs
		618156 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		K2C4_HUMAN (5-476): 1.01e-68: 231: 63.10
+	Hs
		437065 ANDR_HUMAN (172-455): 8.99e-37: 148: 30.16		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		519693 ANDR_HUMAN (172-455): 8.99e-37: 148: 30.16		K2C3_HUMAN (114-461): 7.29e-64: 221: 73.85