HitPredict

Interactor 1: ADT2 (P05141)
ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed]
Gene: SLC25A5

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 758
+	Hs
		496184 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496183 ADT1_HUMAN (1-297): 1.24e-113: 331: 89.23		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581994 ADT2_RAT (1-298): 1.03e-115: 336: 98.66		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94216 ADT2_RAT (1-298): 1.03e-115: 336: 98.66		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Rn
		581991 ADT1_RAT (1-297): 1.45e-114: 334: 89.23		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94213 ADT1_RAT (1-297): 1.45e-114: 334: 89.23		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		497951 ADT2_MOUSE (1-298): 4.76e-116: 337: 98.32		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		497947 ADT1_MOUSE (1-297): 1.18e-114: 334: 89.23		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		497760 S2513_HUMAN (2-104): 5.95e-22: 97.6: 27.18		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		274476 S2512_HUMAN (2-119): 2.57e-20: 92.9: 21.01		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498076 S2512_MOUSE (2-119): 5.28e-20: 91.8: 20.17		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17