Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 7681433, 14681217
Identification Methods affinity chromatography technology, lex-a dimerization assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_2~Integrin_B_tail, I-EGF_1~PSI_integrin, Integrin_beta~Integrin_beta
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000132 - establishment of mitotic spindle orientation
GO:0000287 - magnesium ion binding
GO:0001618 - virus receptor activity
GO:0001701 - in utero embryonic development
and 118 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 798
Hs

1 798
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024