HitPredict

Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0019901 - protein kinase binding GO:0030027 - lamellipodium GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 798 Hs			1 192
+	Hs
		403851 ITB1_HUMAN (1-798): 0: 794: 100.00		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		403770 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03
+	Hs
		403841 ITB1_HUMAN (1-798): 0: 794: 100.00		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		403858 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		403842 ITB1_HUMAN (1-798): 0: 794: 100.00		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		403845 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		403739 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Hs
		574521 ITB5_HUMAN (19-792): 0: 660: 42.64		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		545199 ITB5_HUMAN (19-792): 0: 660: 42.64		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Hs
		436152 ITB5_HUMAN (19-792): 0: 660: 42.64		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Hs
		639928 ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		639922 ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		639924 ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		545674 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Hs
		892650 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		894539 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		901003 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		564491 NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26		RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03
+	Hs
		545337 NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Hs
		436267 NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79