HitPredict

Interactor 1: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Interactor 2: PHF20 (Q9BVI0)
PHD finger protein 20 (Glioma-expressed antigen 2) (Hepatocellular carcinoma-associated antigen 58) (Novel zinc finger protein) (Transcription factor TZP)
Gene: PHF20

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4911 Hs			1 1012
+	Hs
		68299 KMT2C_HUMAN (1-4911): 0: 2416: 100.00		P20L1_HUMAN (1-1011): 0: 787: 33.36
+	Hs
		165712 SET1A_HUMAN (4638-4911): 3.38e-54: 214: 29.73		PHF20_HUMAN (1-1012): 0: 1058: 100.00
+	Hs
		975316 KMT2A_HUMAN (159-332): 7.57e-32: 140: 22.16		PHF20_HUMAN (1-1012): 0: 1058: 100.00
+	Hs
		1313852 SET1B_HUMAN (4778-4911): 3.56e-24: 115: 51.11		PHF20_HUMAN (1-1012): 0: 1058: 100.00
+	Hs
		68263 SET1A_HUMAN (4638-4911): 3.38e-54: 214: 29.73		P20L1_HUMAN (1-1011): 0: 787: 33.36
+	Hs
		68291 CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56		P20L1_HUMAN (1-1011): 0: 787: 33.36
+	Hs
		68286 KMT2A_HUMAN (159-332): 7.57e-32: 140: 22.16		P20L1_HUMAN (1-1011): 0: 787: 33.36
+	Hs
		68287 CHD3_HUMAN (390-526): 1.86e-31: 139: 21.38		P20L1_HUMAN (1-1011): 0: 787: 33.36
+	Hs
		68329 SET1B_HUMAN (4778-4911): 3.56e-24: 115: 51.11		P20L1_HUMAN (1-1011): 0: 787: 33.36
+	Hs
		1017304 EZH2_HUMAN (4563-4893): 4.31e-83: 294: 20.99		BPTF_HUMAN (147-701): 2.86e-32: 138: 10.85
+	Hs
		203729 SUV91_HUMAN (4579-4910): 8.61e-90: 302: 19.18		PHF13_HUMAN (571-706): 2.58e-19: 91.7: 21.23
+	Hs
		1017344 NSD3_HUMAN (1-668): 2.87e-64: 246: 13.52		BPTF_HUMAN (147-701): 2.86e-32: 138: 10.85
+	Hs
		1271101 EZH1_HUMAN (4566-4893): 1.5e-81: 289: 20.97		DIDO1_HUMAN (494-714): 1.75e-16: 87.1: 18.07
+	Hs
		331812 NSD2_HUMAN (31-633): 2.18e-72: 272: 13.39		MDC1_HUMAN (133-612): 5.81e-09: 62.6: 9.67
+	Hs
		1017295 CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56		BPTF_HUMAN (147-701): 2.86e-32: 138: 10.85
+	Hs
		1017286 CHD3_HUMAN (390-526): 1.86e-31: 139: 21.38		BPTF_HUMAN (147-701): 2.86e-32: 138: 10.85
+	Hs
		1059764 CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56		TITIN_HUMAN (63-610): 4.73e-09: 63.2: 12.17
+	Hs
		1056830 CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56		MDC1_HUMAN (133-612): 5.81e-09: 62.6: 9.67
+	Hs
		975294 KMT2A_HUMAN (159-332): 7.57e-32: 140: 22.16		TITIN_HUMAN (63-610): 4.73e-09: 63.2: 12.17
+	Dm
		594814 TRX_DROME (36-334): 3.76e-23: 112: 18.38		ASH1_DROME (602-705): 1.99e-17: 90.4: 25.00