HitPredict

Interactor 1: AFF1 (P51825)
AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)
Gene: AFF1

Interactor 2: ELL3 (Q9HB65)
RNA polymerase II elongation factor ELL3
Gene: ELL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AF-4~Occludin_ELL
Common GO terms	GO:0008023 - transcription elongation factor complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 397
+	Hs
		1335107 AFF4_HUMAN (10-1208): 2.3e-90: 318: 34.44		ELL3_HUMAN (1-397): 0: 614: 100.00
+	Hs
		130150 AFF1_HUMAN (1-1210): 3.61e-130: 431: 100.00		ELL2_HUMAN (239-397): 5.38e-56: 196: 38.99
+	Hs
		850803 AFF1_HUMAN (1-1210): 3.61e-130: 431: 100.00		ELL_HUMAN (243-397): 4.35e-53: 188: 34.16
+	Hs
		130172 AFF4_HUMAN (10-1208): 2.3e-90: 318: 34.44		ELL2_HUMAN (239-397): 5.38e-56: 196: 38.99
+	Hs
		876672 AFF4_HUMAN (10-1208): 2.3e-90: 318: 34.44		ELL_HUMAN (243-397): 4.35e-53: 188: 34.16
+	Rn
		94332 F1M4A0_RAT (75-732): 2.06e-43: 175: 15.78		OCLN_RAT (128-394): 7.47e-80: 256: 21.56
+	Mm
		761855 ZO1_MOUSE (76-734): 7.98e-42: 170: 15.11		OCLN_MOUSE (128-394): 1.28e-81: 260: 20.82
+	Hs
		297831 K0754_HUMAN (277-807): 6.55e-29: 128: 12.75		OCLN_HUMAN (128-394): 1.08e-87: 276: 22.59
+	Hs
		1084068 MICA3_HUMAN (92-811): 7.34e-10: 65.8: 11.23		OCLN_HUMAN (128-394): 1.08e-87: 276: 22.59
+	Hs
		130165 Q8TAX5_HUMAN (10-402): 2.53e-29: 123: 38.83		ELL2_HUMAN (239-397): 5.38e-56: 196: 38.99
+	Dm
		1372607 AFFL_DROME (276-1210): 7.43e-31: 134: 16.27		ELL_DROME (115-392): 3.48e-37: 145: 21.35