HitPredict

Interactor 1: AFF1 (P51825)
AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)
Gene: AFF1

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 530
+	Hs
		370646 AFF4_HUMAN (10-1208): 2.3e-90: 318: 34.44		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1154059 NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		659745 AFF4_HUMAN (10-1208): 2.3e-90: 318: 34.44		RXRB_HUMAN (96-498): 2.03e-108: 335: 27.05
+	Hs
		369815 NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1270066 PCLO_HUMAN (46-1110): 1.02e-32: 140: 10.07		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269591 TARA_HUMAN (19-1006): 9.21e-18: 91.7: 7.94		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		152674 KMT2D_HUMAN (357-1098): 8.96e-12: 72.4: 9.13		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377487 AN36B_HUMAN (724-1142): 9.59e-52: 201: 14.42		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		782571 NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377401 NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Mm
		101423 F8VPR5_MOUSE (72-770): 3.98e-28: 125: 11.92		ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72
+	Hs
		370417 TARA_HUMAN (19-1006): 9.21e-18: 91.7: 7.94		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		152573 KMT2D_HUMAN (357-1098): 8.96e-12: 72.4: 9.13		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369607 MDC1_HUMAN (161-949): 1.95e-10: 67.6: 10.79		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		101427 F8VPR5_MOUSE (72-770): 3.98e-28: 125: 11.92		RXRG_MOUSE (13-499): 5.3e-117: 355: 22.56
+	Hs
		487818 AFF4_HUMAN (10-1208): 2.3e-90: 318: 34.44		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		152605 KMT2D_HUMAN (357-1098): 8.96e-12: 72.4: 9.13		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		152574 KMT2D_HUMAN (357-1098): 8.96e-12: 72.4: 9.13		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487522 NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		152579 KMT2D_HUMAN (357-1098): 8.96e-12: 72.4: 9.13		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59