HitPredict

Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: CLCC1 (Q96S66)
Chloride channel CLIC-like protein 1 (Mid-1-related chloride channel protein 1)
Gene: CLCC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1382 Hs			1 551
+	Hs
		435735 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		537766 INSRR_HUMAN (13-1341): 0: 1293: 51.12		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		872474 EPHA5_HUMAN (567-1319): 1.23e-176: 555: 20.98		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		665517 EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		445872 ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		383944 ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		1301880 ALK_HUMAN (982-1339): 1.96e-70: 263: 40.53		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		169197 MUSK_HUMAN (1017-1291): 1.24e-69: 254: 42.22		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		385383 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		1081573 NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43		CLCC1_HUMAN (1-551): 0: 1108: 100.00