Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 8650207
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0035556 - intracellular signal transduction
GO:0042169 - SH2 domain binding
GO:0070062 - extracellular exosome
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 509
Hs

1 440
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024