HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36490346
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 1102
+	Hs
		412293 FYN_HUMAN (30-507): 0: 586: 59.01		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		523098 SRC_HUMAN (20-507): 0: 586: 55.00		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		337522 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		523210 SRC_HUMAN (20-507): 0: 586: 55.00		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Hs
		846546 BLK_HUMAN (1-509): 0: 557: 59.35		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Hs
		64203 BLK_HUMAN (1-509): 0: 557: 59.35		UBP27_HUMAN (187-521): 3.14e-90: 298: 20.05
+	Ce
		60979 SRC2_CAEEL (35-507): 0: 526: 47.71		A5PEX6_CAEEL (61-200): 1.57e-28: 126: 42.66
+	Ce
		60975 SRC1_CAEEL (1-508): 8.64e-179: 514: 44.84		A5PEX6_CAEEL (61-200): 1.57e-28: 126: 42.66