HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: CD226 (Q15762)
CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)
Gene: CD226

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10591186
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045121 - membrane raft
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 537 Hs			1 336
+	Hs
		433317 YES_HUMAN (1-537): 0: 591: 71.61		CXAR_HUMAN (1-335): 1.95e-47: 165: 15.56
+	Hs
		507818 SRC_HUMAN (1-537): 0: 598: 68.21		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Hs
		433229 YES_HUMAN (1-537): 0: 591: 71.61		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Hs
		412008 FYN_HUMAN (1-537): 0: 643: 100.00		FGFR2_HUMAN (14-333): 2.36e-16: 82: 13.47
+	Hs
		412060 FYN_HUMAN (1-537): 0: 643: 100.00		VGFR2_HUMAN (25-265): 9.67e-15: 77.3: 14.18
+	Hs
		433691 LYN_HUMAN (1-535): 0: 535: 54.48		CXAR_HUMAN (1-335): 1.95e-47: 165: 15.56
+	Hs
		523211 SRC_HUMAN (1-537): 0: 598: 68.21		TUTLB_HUMAN (8-253): 1.26e-19: 92: 12.50
+	Hs
		433507 YES_HUMAN (1-537): 0: 591: 71.61		TUTLB_HUMAN (8-253): 1.26e-19: 92: 12.50
+	Hs
		433928 LYN_HUMAN (1-535): 0: 535: 54.48		NECT2_HUMAN (20-189): 7.01e-39: 146: 17.17
+	Hs
		522773 SRC_HUMAN (1-537): 0: 598: 68.21		FGFR2_HUMAN (14-333): 2.36e-16: 82: 13.47
+	Hs
		522825 SRC_HUMAN (1-537): 0: 598: 68.21		VGFR2_HUMAN (25-265): 9.67e-15: 77.3: 14.18
+	Hs
		507897 ABL2_HUMAN (7-537): 2.06e-170: 515: 38.09		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Hs
		507964 ITK_HUMAN (4-526): 5.88e-165: 483: 31.90		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Hs
		434081 LYN_HUMAN (1-535): 0: 535: 54.48		TUTLB_HUMAN (8-253): 1.26e-19: 92: 12.50
+	Hs
		433573 LYN_HUMAN (1-535): 0: 535: 54.48		FGFR2_HUMAN (14-333): 2.36e-16: 82: 13.47
+	Hs
		484330 SRMS_HUMAN (50-528): 3.37e-152: 446: 39.00		VSIG8_HUMAN (8-273): 1.97e-40: 148: 15.17
+	Hs
		507989 PTK6_HUMAN (83-529): 4.09e-152: 444: 42.92		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Dm
		219802 ABL_DROME (4-537): 3.97e-166: 513: 38.01		O44924_DROME (14-231): 1.07e-09: 61.9: 12.22
+	Hs
		789014 TEC_HUMAN (5-529): 6.12e-163: 478: 34.89		TUTLB_HUMAN (8-253): 1.26e-19: 92: 12.50