Protein: SYT11
Synaptotagmin-11 (Synaptotagmin XI) (SytXI)

Gene: SYT11
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q9BT88

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0001778 - plasma membrane repair
GO:0001818 - negative regulation of cytokine production
GO:0001891 - phagocytic cup
GO:0005544 - calcium-dependent phospholipid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1413254

PDLI7
PDZ and LIM domain protein 7

3

1

High-throughput

0.667

High

226870

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

4

3

High-throughput

0.642

High

242759

PRKN
E3 ubiquitin-protein ligase parkin

2

4

Small-scale

0.639

High

1405799

TTC1
Tetratricopeptide repeat protein 1

4

4

High-throughput

0.630

High

845779

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.618

High

725449

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

2

High-throughput

0.611

High

1393035

PDLI5
PDZ and LIM domain protein 5

2

1

High-throughput

0.611

High

1365969

APBP2
Amyloid protein-binding protein 2

2

1

High-throughput

0.584

High

1413252

AT132
Polyamine-transporting ATPase 13A2

1

2

Small-scale

0.582

High

1288915

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

16

High-throughput

0.575

High

1389494

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

3

High-throughput

0.553

High

1400121

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.546

High

163352

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

1

High-throughput

0.536

High

522728

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

1

High-throughput

0.536

High

658767

JAK1
Tyrosine-protein kinase JAK1

1

7

High-throughput

0.536

High

661326

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

1

High-throughput

0.536

High

1063012

DDR1
Epithelial discoidin domain-containing receptor 1

1

8

High-throughput

0.536

High

1102748

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

1

High-throughput

0.536

High

1278314

LRP10
Low-density lipoprotein receptor-related protein 10

1

5

High-throughput

0.536

High

1403975

SCN2A
Sodium channel protein type 2 subunit alpha

1

12

High-throughput

0.536

High

1413251

GPR35
G-protein coupled receptor 35

1

0

High-throughput

0.518

High

516716

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

3

High-throughput

0.514

High

787338

ACV1B
Activin receptor type-1B

1

0

High-throughput

0.513

High

1115968

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.513

High

1357039

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.513

High

1399265

HUTI
Probable imidazolonepropionase

1

0

High-throughput

0.513

High

412528

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

1270967

RHOU
Rho-related GTP-binding protein RhoU

1

3

High-throughput

0.479

High

1413257

ALK
ALK tyrosine kinase receptor

1

5

High-throughput

0.479

High

560499

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

1056940

FMR1
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.457

High

208558

PJA2
E3 ubiquitin-protein ligase Praja-2

1

1

High-throughput

0.445

High

230661

PRIC3
Prickle planar cell polarity protein 3

1

3

High-throughput

0.445

High

255192

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

324034

CSTN1
Calsyntenin-1

1

5

High-throughput

0.445

High

484216

PGFRB
Platelet-derived growth factor receptor beta

1

1

High-throughput

0.445

High

748659

DSG3
Desmoglein-3

1

2

High-throughput

0.445

High

1022524

VLDLR
Very low-density lipoprotein receptor

1

4

High-throughput

0.445

High

1114157

CUL3
Cullin-3

1

4

High-throughput

0.445

High

1119282

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

12

High-throughput

0.445

High

1199674

KLH22
Kelch-like protein 22

1

2

High-throughput

0.445

High

1213688

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

5

High-throughput

0.445

High

1286465

DSG4
Desmoglein-4

1

2

High-throughput

0.445

High

1413256

CCG5
Voltage-dependent calcium channel gamma-5 subunit

1

1

High-throughput

0.445

High

1413258

ITM2B
Integral membrane protein 2B

1

5

High-throughput

0.445

High

1413262

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.445

High

1255304

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1413247

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.437

High

165821

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

0

High-throughput

0.426

High

261652

CATL2
Cathepsin L2

1

0

High-throughput

0.426

High

296374

ATRN
Attractin

1

0

High-throughput

0.426

High

669357

ACKR3
Atypical chemokine receptor 3

1

0

High-throughput

0.426

High

692260

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.426

High

885603

PRI2
DNA primase large subunit

1

0

High-throughput

0.426

High

1177190

MICB
MHC class I polypeptide-related sequence B

1

0

High-throughput

0.426

High

1186428

ASTRB
Protein Aster-B

1

0

High-throughput

0.426

High

1339395

GP156
Probable G-protein coupled receptor 156

1

0

High-throughput

0.426

High

1353655

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.426

High

1355924

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.426

High

1413246

TMM59
Transmembrane protein 59

1

0

High-throughput

0.426

High

1413261

PCDG5
Protocadherin gamma-A5

1

0

High-throughput

0.426

High

1413248

PCX3
Pecanex-like protein 3

1

1

High-throughput

0.407

High

1413253

ISK5
Serine protease inhibitor Kazal-type 5

1

1

High-throughput

0.407

High

1413255

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

1

1

High-throughput

0.407

High

876982

KC1A
Casein kinase I isoform alpha

1

1

Small-scale

0.390

High

1413250

ZBT20
Zinc finger and BTB domain-containing protein 20

2

0

High-throughput

0.313

High

787702

SPB5
Serpin B5

1

0

High-throughput

0.232

Low

1010098

DLK1
Protein delta homolog 1

1

0

High-throughput

0.232

Low

1154344

CYTM
Cystatin-M

1

0

High-throughput

0.232

Low

1413249

ZDH11
Palmitoyltransferase ZDHHC11

1

0

High-throughput

0.232

Low

1413259

TMED5
Transmembrane emp24 domain-containing protein 5

1

0

High-throughput

0.232

Low

1413260

DCAF1
DDB1- and CUL4-associated factor 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025