HitPredict

Interactor 1: CDC7 (P06243)
Cell division control protein 7 (EC 2.7.11.1)
Gene: CDC7

Interactor 2: CDC53 (Q12018)
Cell division control protein 53 (Cullin-A) (E3 ubiquitin ligase complex SCF subunit CDC53)
Gene: CDC53

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.595

Property	Details
Experiments	10688190, 11283612
Identification Methods	two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 507 Sc			1 815
+	Hs
		681835 AKT1_HUMAN (3-381): 4.14e-106: 326: 11.17		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		981052 KPCT_HUMAN (13-378): 4.99e-105: 331: 11.38		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		568656 KAPCA_HUMAN (3-365): 7.42e-106: 321: 11.92		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		609667 KAPCG_HUMAN (2-365): 2.07e-105: 320: 11.89		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		325719 LATS1_HUMAN (16-434): 3.63e-63: 224: 18.25		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		625416 CDK2_HUMAN (31-324): 4.65e-62: 206: 20.59		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		960092 CDK3_HUMAN (31-188): 4.08e-58: 196: 31.74		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		325721 LATS1_HUMAN (16-434): 3.63e-63: 224: 18.25		CUL4A_HUMAN (6-815): 0: 701: 21.29
+	Hs
		325720 LATS1_HUMAN (16-434): 3.63e-63: 224: 18.25		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		625417 CDK2_HUMAN (31-324): 4.65e-62: 206: 20.59		CUL4B_HUMAN (5-815): 0: 695: 21.14
+	Hs
		125882 CDC7_HUMAN (270-473): 2.17e-34: 138: 26.39		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		1041287 AKT3_HUMAN (240-449): 2.63e-18: 89.6: 11.32		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		682174 AKT2_HUMAN (212-440): 5.05e-16: 82.3: 11.26		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		414908 CDK1_HUMAN (236-339): 6.62e-12: 68.4: 23.81		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		586736 CSK22_HUMAN (28-187): 6.27e-12: 68.9: 31.71		CUL4A_HUMAN (6-815): 0: 701: 21.29
+	Hs
		586735 CSK22_HUMAN (28-187): 6.27e-12: 68.9: 31.71		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		414909 CDK1_HUMAN (236-339): 6.62e-12: 68.4: 23.81		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		586737 CSK22_HUMAN (28-187): 6.27e-12: 68.9: 31.71		CUL4B_HUMAN (5-815): 0: 695: 21.14
+	Hs
		960361 CDK16_HUMAN (33-189): 2.98e-11: 67.4: 31.10		CUL3_HUMAN (10-815): 0: 696: 21.12