HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TRI29 (Q14134)
Tripartite motif-containing protein 29 (Ataxia telangiectasia group D-associated protein)
Gene: TRIM29

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20368352
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0002039 - p53 binding GO:0008270 - zinc ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 588
+	Hs
		413166 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (149-588): 2.96e-116: 355: 17.40
+	Hs
		413111 P53_HUMAN (1-393): 0: 619: 100.00		TRI27_HUMAN (140-571): 3.4e-107: 333: 16.04
+	Hs
		414669 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (148-588): 5.44e-106: 330: 15.15
+	Hs
		414136 P53_HUMAN (1-393): 0: 619: 100.00		TRI69_HUMAN (151-588): 1.34e-94: 300: 13.15
+	Hs
		279018 P53_HUMAN (1-393): 0: 619: 100.00		TRIM3_HUMAN (136-531): 1.73e-72: 248: 15.97
+	Hs
		414641 P53_HUMAN (1-393): 0: 619: 100.00		TRI45_HUMAN (56-532): 1.79e-72: 244: 12.67
+	Hs
		414564 P53_HUMAN (1-393): 0: 619: 100.00		TRIM8_HUMAN (116-531): 2.99e-71: 240: 16.77
+	Hs
		413940 P53_HUMAN (1-393): 0: 619: 100.00		LIN41_HUMAN (173-547): 5.74e-62: 221: 15.48
+	Hs
		413823 P53_HUMAN (1-393): 0: 619: 100.00		TRI25_HUMAN (104-446): 1.29e-61: 216: 22.54
+	Hs
		414426 P53_HUMAN (1-393): 0: 619: 100.00		TRI47_HUMAN (108-376): 5.08e-55: 198: 27.66
+	Hs
		414049 P53_HUMAN (1-393): 0: 619: 100.00		TRI65_HUMAN (168-384): 2.34e-47: 175: 23.51
+	Hs
		414293 P53_HUMAN (1-393): 0: 619: 100.00		TRI41_HUMAN (182-393): 1.79e-41: 160: 22.07