HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ASPM (Q8IZT6)
Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)
Gene: ASPM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32807901, 20308539
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 3477
+	Hs
		186772 P73_HUMAN (13-362): 2.36e-166: 481: 39.74		ASPM_HUMAN (1-3477): 0: 2235: 100.00
+	Hs
		1316881 P63_HUMAN (28-363): 2.36e-145: 429: 42.11		ASPM_HUMAN (1-3477): 0: 2235: 100.00
+	Hs
		414685 P53_HUMAN (1-393): 0: 619: 100.00		MYO5C_HUMAN (2658-3307): 6.48e-23: 110: 10.82
+	Hs
		414821 P53_HUMAN (1-393): 0: 619: 100.00		MYH13_HUMAN (1939-3021): 7.48e-22: 107: 9.03
+	Hs
		414928 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (1941-3019): 2.64e-21: 105: 6.69
+	Hs
		413870 P53_HUMAN (1-393): 0: 619: 100.00		PLEC_HUMAN (2048-3476): 2e-19: 99.4: 7.47
+	Hs
		414835 P53_HUMAN (1-393): 0: 619: 100.00		MYO5B_HUMAN (1256-1945): 6.31e-14: 81.1: 13.87
+	Hs
		413639 P53_HUMAN (1-393): 0: 619: 100.00		SPTB2_HUMAN (2115-3392): 2.01e-11: 72.9: 7.71
+	Hs
		73985 P53_HUMAN (1-393): 0: 619: 100.00		MYO9A_HUMAN (2899-3171): 1.61e-09: 66.4: 19.15
+	Dm
		1445154 Q9N6D8_DROME (124-325): 3.12e-77: 245: 24.31		ASP_DROME (2489-3383): 5.16e-10: 68.2: 11.31