Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 30137413, 32707033, 23602568
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, pull down, tandem affinity purification, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 928
Hs

1 763
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024