Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.704

The method score is based on:

Property Details
Experiments 10490602, 11593423, 11583987, 17827154, 10228159
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
and 5 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 928
Hs

1 488
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024