HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 25277244, 28130664, 30385828, 32417755, 39358380, 22365833, 10383393, 11003656, 15581903, 25036637
Identification Methods two hybrid, pull down, cross-linking study, cosedimentation in solution, reverse ras recruitment system, luminescence based mammalian interactome mapping
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP20~HSP20
Common GO terms GO:0000502 - proteasome complex
GO:0001533 - cornified envelope
GO:0001932 - regulation of protein phosphorylation
GO:0003723 - RNA binding
GO:0005080 - protein kinase C binding
and 37 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 205
Hs

1 205
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025