HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: JUNB (P17275)
Transcription factor JunB (Transcription factor AP-1 subunit JunB)
Gene: JUNB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 347
+	Mm
		404129 TPM1_MOUSE (2-285): 2.33e-44: 153: 91.55		JUN_MOUSE (1-347): 8.87e-57: 189: 44.32
+	Hs
		401268 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		JUN_HUMAN (1-347): 5.04e-56: 187: 43.89
+	Hs
		401292 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		JUN_HUMAN (1-347): 5.04e-56: 187: 43.89
+	Mm
		404130 TPM2_MOUSE (2-285): 1.89e-39: 140: 86.62		JUN_MOUSE (1-347): 8.87e-57: 189: 44.32
+	Hs
		3155 A0A0S2Z4G4_HUMAN (44-285): 5.8e-36: 130: 72.31		JUN_HUMAN (1-347): 5.04e-56: 187: 43.89
+	Hs
		418871 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		JUND_HUMAN (5-347): 4.93e-44: 156: 39.12
+	Hs
		451187 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		JUND_HUMAN (5-347): 4.93e-44: 156: 39.12
+	Hs
		418865 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		ATF2_HUMAN (20-347): 9.06e-36: 137: 15.94
+	Hs
		451186 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		ATF2_HUMAN (20-347): 9.06e-36: 137: 15.94
+	Dm
		419095 TPM1_DROME (2-282): 8.67e-51: 171: 45.97		JRA_DROME (33-340): 1.05e-28: 114: 28.71
+	Hs
		547777 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		ATF2_HUMAN (20-347): 9.06e-36: 137: 15.94