HitPredict

Interactor 1: ITAV (P06756)
Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]
Gene: ITGAV

Interactor 2: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1048 Hs			1 227
+	Hs
		419187 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RND3_HUMAN (4-227): 3.64e-100: 292: 64.00
+	Hs
		419227 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RND1_HUMAN (6-227): 1.9e-83: 249: 53.15
+	Hs
		419186 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		419135 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		419189 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		419184 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86
+	Hs
		419149 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		419191 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOG_HUMAN (7-193): 2.82e-75: 227: 41.71
+	Hs
		419188 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		120277 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48
+	Hs
		419238 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOF_HUMAN (9-191): 9.16e-51: 165: 43.01
+	Hs
		443056 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RND2_HUMAN (1-227): 7.71e-110: 316: 100.00
+	Hs
		443064 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RND3_HUMAN (4-227): 3.64e-100: 292: 64.00
+	Hs
		443063 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		436126 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		443068 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		443059 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86
+	Hs
		443028 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		443066 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		120283 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48