Interactor 1: H2A1 (P04911)
Histone H2A.1
Gene: HTA1
Interactor 2: SIR2 (P06700)
NAD-dependent histone deacetylase SIR2 (EC 2.3.1.286) (Regulatory protein SIR2) (Silent information regulator 2)
Gene: SIR2
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19217406 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Histone~SIR2, Histone_H2A_C~SIR2 |
| Common GO terms | GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0031507 - heterochromatin formation |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
